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Inflammation and Depression

Dahlia 'Inflammation'

Dahlia ‘Inflammation’ (Photo credit: F. D. Richards)

According to this Danish post, inflammation causes depression, which causes inflammation.  Depression causes one to have errant sleep, poor stress management, eating poorly, withdrawl from socials support.  This causes epigenetic changes that increase inflammation.

Danish scientists took a cohort of 73,000 people and measured their levels of C-Reactive Protein (CRP)…a marker for inflammation, and mapped those levels to antidepressant dispensation from a pharmacy, and records of people hospitalized for depression.  (You will never be able to do something like this in the USA). 

They found that people with CRP above 3mg/liter had more antidepressant use and hospitalization than those with values under 1mg/liter.  CRP is made in the liver. While the article says that inflammation may affect serotonin in the brain.  We know that serotonin is also found in the GI tract….right next to that liver.  So it must be affected there as well?

 So many more reasons to monitor inflammation, and reduce it.   I suspect that inflammation is our body overextended.  Designed to solve problems here and there such as in injuries, prolonged stress may lead to continuous inflammation.  So stress reduction may be a great way to reduce CRP and maybe therefore depression..

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